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Super B-Complex - High Absorption Methylated B Vitamins, Clean Label, Sustained Release - Complete Spectrum of B Vitamins with Folate, Boosted B12 & Vitamin C, 60 Tablets, by Igennus

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methyltetrahydrofolate helps convert the amino acid homocysteine down to another essential amino acid, methionine, which is used by your body to make proteins, utilize antioxidants, and to assist your liver to process fats. Methionine helps with depression and even inflammation. It also helps convert estradiol (E2) into estriol (E3)! For most healthy individuals eating a well-balanced diet, B-complex supplements are not necessary. B vitamins are found in a wide variety of foods in different amounts, including leafy greens, salmon, legumes, eggs, milk, beef, and whole grains. Pregnant people and people who are lactating: Multivitamins during pregnancy are effective in helping reduce the risk of birth defects and other negative birth outcomes and can help lactating women achieve their higher nutrient needs while breastfeeding. Needs during pregnancy and while breastfeeding are different from other adults, so it’s best to choose a prenatal-specific multivitamin. MTHFR 677CT + MTHFR 1298AC = a compound heterozygous variant which is one variant from two different parts of the gene – this seems to be the worst form of the variant.

This supplement provides vitamin B12 in the form of cyanocobalamin. In addition to the B vitamins, it contains 75 milligrams of spirulina, a type of blue green algae that contains protein, omega-3 fatty acids, and antioxidants. While the amount of spirulina in this supplement may be too low to have any effect, spirulina may lower blood pressure, slow blood clotting, increase immune system activity, and lower blood sugar. Please talk to a healthcare provider before starting this supplement if you are taking medication for diabetes, immunosuppressants, or anticoagulants. I recommend everyone take methylated B vitamins regardless of whether they have the mutation or not. That way they are guaranteed to be getting the most effective form of the vitamin. A caveat though – not everyone with the mutation should take methylated B12 – I also take Hydroxy and Adenosylcobalamin because I get anxiety on methylated B 12. This requires working with a functional doctor or genetic specialist who can do more specific testing and determine the right course of action for your needs. However, there are some people that may benefit from a B complex supplement, including those with limited diets, older adults, those with gastrointestinal conditions, pregnant people, and people who have undergone bariatric surgery. Some may just need to supplement with one or two B vitamins rather than taking the entire B-complex, so it is important to talk with a healthcare provider to assess your individual needs.

I often recommend supplements with the methylated (active) forms of the key B vitamins but PLEASE NOTE, these may not work for you depending on the type of variant you have. If you are double homozygous (both your MTHFR genes are variants), methyl folate and methyl-B12 supplementation can cause problems for you. Also, you should not consume high doses of niacin (vitamin B3), because it can hinder methylation. Separately, as of November 2022, the FDA prohibits nicotinamide mononucleotide (NMN) to be sold as a supplement while they investigate its potential usage as a drug. Because this mandate is new, you will likely still see this ingredient on the market until the regulation is fully enforced. The B-complex vitamins we recommend in this article do not contain nicotinamide riboside (NR) or nicotinamide mononucleotide (NMN).

Vitamin C Fact Sheet for Health Professionals. National Institutes of Health Office of Dietary Supplements. This supplement may be especially beneficial for women with premenstrual syndrome (PMS). Vitamin B6 is involved in neurotransmitter synthesis, which is essential for mood and stress support. Some research has shown supplemental B6 to relieve premenstrual symptoms. The first thing you need to do is avoid any supplements that have synthetic forms of the B vitamins in them. For instance, any supplement with folic acid is no good – this is just the synthetic, inactive form of folate. For consumers who need to follow a gluten-free diet, it is important that supplements are also gluten-free. This Fermented Vitamin B Complex supplement by New Chapter is certified gluten-free by NSF. It’s also USDA Certified Organic and Non-GMO Project Verified. Each tablet provides all eight B vitamins, ranging from 100% to 500% of your daily needs.

Additionally, vitamins in these groups act as facilitators and help most other systems in the body perform their duties efficiently. Since methyl-related vitamins have a direct impact on the metabolism as well as the detoxification of hormonal pathways, they also aid with the absorption and impact of any nutrient that is taken alongside it, even beyond methyl groups. The FDA does not evaluate any supplements for safety and effectiveness before they go to market, including B-complex supplements. Some of the B vitamins may interfere with certain medications. For example, folate may reduce the effectiveness of methotrexate (used to treat certain cancers and autoimmune diseases) and some antiepileptic drugs. It is important to consult with a healthcare professional before beginning any supplementation routine, especially if you are taking any medications. Because iron-deficiency anemia is rare among men, this multivitamin doesn’t contain iron, which means less chance of digestive upset or constipation. Para-aminobenzoic acid (PABA) is often referred to as vitamin B10 and may be in some B-complex supplements. PABA is also found in some sunscreens, as it has been shown to absorb UV rays. While PABA is called a B vitamin, it is not currently considered an essential nutrient we need to get in the diet.

This prenatal vitamin does not contain iron or omega-3s, which you may want to consider taking separately, depending on your diet and nutritional status. FullWell does offer a fish-oil supplement to complement their multivitamin, which contains 550 milligrams of omega-3 fatty acids, including both EPA and DHA. Roberts JE, Dennison J. The photobiology of lutein and zeaxanthin in the eye. J Ophthalmol. 2015;2015:687173. doi:10.1155/2015/687173 We support supplements that are evidence-based and rooted in science. We value certain product attributes that we find to be associated with the highest quality products. We also consulted with these nutrition experts for their valued opinions on what to consider when shopping for B-complex supplements:If you experience any negative effects – severe anxiety, panic, headaches, migraines, insomnia, palpitations, rash and achy joints – please discontinue use of methyl-folate products and seek the help of a trained practitioner who can help you get to the root cause. People looking to support wound healing or prevent canker sores: In addition to their basic everyday functions, research shows the important role that B vitamins play in wound healing. Thiamine is particularly vital to promote wound healing and increase breaking strength during healing. There is also evidence to support B-complex supplementation to help prevent recurring canker sores in the mouth, particularly with vitamin B12. Methylated vitamins work in a similar fashion. They are already in their active state, so the rate at which they can be absorbed by the body is much greater than unmethylated vitamins, which means the body can utilize those nutrients faster. Should I take a daily multivitamin? The Nutrition Source. Harvard T.H. Chan School of Public Health. National Institutes of Health Office of Dietary Supplements. Vitamin B6: Fact sheet for health professionals.

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