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Molecular Biology of the Cell

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It describes the current understanding of cell biology and includes basic biochemistry, experimental methods for investigating cells, the properties common to most eukaryotic cells, the expression and transmission of genetic information, the internal organization of cells, and the behaviour of cells in multicellular organisms. Bruce Alberts, Alexander Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter, editors.

Is there any huge difference between the 5th Edition and the 6th Edition of “Molecular Biology of the Cell” by Bruce Alberts, besides the different problems and 1 or 2 new chapters. These documents also describe distinctive dependencies, making text-mining in molecular biology a specific discipline.Importantly, the information is also very much up to date: for example, the regulation of gene expression by noncoding RNAs is explained in detail, including the roles of small and long noncoding RNAs as well as the bacterial CRISPR system. Since 1985, the authors of the Molecular Biology of the Cell have gathered at this 19th century home in St. The book was the first to position cell biology as a central discipline for biology and medicine, and immediately became a landmark textbook. Photographs are often used to translate diagrams and schematics into the real world and, incidentally, help demonstrate how beautiful nature is at the sub-microscopic level.

Although the chapters of this book can be read independently of one another, they are arranged in a logical sequence of five parts.

Huge amounts of electronic biomedical documents, such as molecular biology reports or genomic papers are generated daily. Written in a readable style, with consistently excellent illustrations, it covers a breadth and depth of information that is truly impressive.

I also very much like the fact that questions are not just answered, but that there are a large number of relevant references associated with these answers. It demonstrates how mathematical analysis of the dynamics of molecular interactions such as those regulating gene expression can highlight the roles played by protein/promoter and protein/protein interaction as well as protein stability in generating or repressing transcriptional signals.From left: Bruce Alberts, Keith Roberts, Martin Raff, Gavin Borden (publisher), James Watson, Dennis Bray and Julian Lewis. I also particularly enjoyed the detailed information provided on the complicated issue of stem cells in the intestine in Chapter 22, together with wonderful illustrations and photographs.

The book continues with detailed information on cellular organisation and structure as well as interaction of multicellular organisms and ends with descriptions of pathogens and the workings of the immune system. My only criticism is that the answers to the problems posed in the textbook are also answered here (over the last 150 pages), making it necessary to acquire both books. The textbook is complemented by an equally comprehensive problems book, which “aims to help students appreciate the ways in which understanding of how cells work…can be further explored through experiments and simple calculations”.I am especially impressed by the grouping of relevant information about any topic in panels, which convey in clear language and superb illustrations the basic knowledge required to understand that topic. Now in it’s 6th edition, Molecular Biology of the Cell(MBoC), a classic university biology textbook, and it’s lighter companion book, Essential Cell Biology (in its 4th edition), continue to offer students a “new and invigorating outlook on what cells are and what they do. Furthermore, the competition from freely and instantly accessible online information requires any such book to offer a unique and cost-effective solution to the needs of impecunious (at least as far as study-associated expenses are concerned) students. The usual computational tools of Natural Language Processing cannot be readily applied to extract these biomedical events, due to the peculiarities of the domain.

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