Liquipak BAC 50 - Benzalkonium Chloride Concentrated 5L

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CAS RN: 91080-30-7; Chemical Name: Quaternary ammonium compounds, benzyl-C10-21-alkyldimethyl,chlorides; Synonyms: benzyl-C10-21 -alkyldimethylammonium chloride

In Russia and China, benzalkonium chloride is used as a contraceptive. Tablets are inserted vaginally, or a gel is applied, resulting in local spermicidal contraception. Formulation techniques have been used to great effect in enhancing the virucidal activity of quaternary ammonium-based disinfectants such as Virucide 100 to typical healthcare infection hazards such as hepatitis and HIV.[citation needed] International Programme on Chemical Safety, Poisons Information Monograph (PIMs) - Benzalkonium Chloride

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https://www.niaaa.nih.gov/health-professionals-communities/core-resource-on-alcohol/basics-defining-how-much-alcohol-too-much KEYWORDS: alkyl dimethyl benzyl ammonium chlorides, antiseptic, BACs, benzalkonium chlorides, QACs, BAC 50

Depending on purity, benzalkonium chloride ranges from colourless to a pale yellow (impure). Benzalkonium chloride is readily soluble in ethanol and acetone. Dissolution in water is ready, upon agitation. Aqueous solutions should be neutral to slightly alkaline. Solutions foam when shaken. Concentrated solutions have a bitter taste and a faint almond-like odour. [ citation needed] As an example, the FDA recently published three proposed and final decisions regarding the use of chemicals as consumer hand rub antiseptics, consumer hand and body wash antiseptics, and health care antiseptics. Benzalkonium chloride is usually non-irritating, and non-sensitizing and is well tolerated in the dilutions normally employed on the skin and mucous membranes.BAC 50 isalso among the most common active ingredients in disinfectants used in residential, industrial, agricultural, and clinical settings. BAC 50 can be used for the preparation of disinfectants, cleansers, and timber preservation formulations and the production of fungicidal/algicidal washes and other similar applications. Due to its antimicrobial activity [21] when applied to skin, some topical medications for acne vulgaris have benzalkonium chloride added to increase the products’ efficiency or shelf-life. [22] [23] They are effective through a wide pH range, are surface active/adhesive cationic agents and do not add unpleasant odour/colour to finished formulations.

BAC 50 is a human skin and severe eye irritant. It is a suspected respiratory toxicant, immunotoxicant, gastrointestinal toxicant, and neurotoxicant. An advantage of benzalkonium chloride, not shared by ethanol-based antiseptics or hydrogen peroxide antiseptics, is that it does not cause a burning sensation when applied to broken skin a b c d Rowe, Raymond (2009). Handbook of Pharmaceutical Excipients 6th Edition. London, UK: Pharmaceutical Press. pp.56–58. ISBN 978-1-58212-135-2. Stability in application: Stable in the presence of light, over the pH range 4 - 10 and up to 120°C

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It is widely used in cosmetics, wet wipes, hand and surface sanitisers. Benzalkonium chloride was found to be an effective method of contraception. Benzalkonium chloride is a human skin and severe eye irritant. [38] It is a respiratory toxicant, immunotoxicant, gastrointestinal toxicant, and neurotoxicant. [39] [40] [41] Benzalkonium chloride is also used in many non-consumer processes and products, including as an active ingredient in surgical disinfection. A comprehensive list of uses includes industrial applications. [9] The National Institute on Alcohol Abuse and Alcoholism (NIAAA) states that any amount of alcohol is “too much” when you’re: Further studies supports the idea of lipid content determining BAC (im)permeability, as species with high lipid content like Mycobacterium tuberculosis were found to be less antiseptic sensitive than Mycobacterium phlei with lower lipid content.