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Godfrey HR, Godfrey NJ, Godfrey JC, Riley D. A randomized clinical trial on the treatment of oral herpes with topical zinc oxide/glycine. Altern Ther Health Med. 2001;7(3):49-56.
Caruso TJ, Prober CG, Gwaltney JM. Treatment of naturally acquired common colds with zinc: a structured review. Clin Infect Dis. 2007;45(5):569-74. Earlier findings indicated involvement of the divalent metal transporter (DMT)-1, which is a cation transporter of low selectivity, in intestinal zinc uptake [ 89]. The identification of ZIP4 as the major transporter for zinc uptake and contradictory results in several in vitro studies [ 90, 91, 92, 93, 94], however, challenge the role of DMT-1 in physiological zinc transport.
4. Zinc Picolinate
Fang X, et al. (2016). Dose-response relationship between dietary magnesium intake and risk of type 2 diabetes mellitus: A systematic review and meta-regression analysis of prospective cohort studies. This is a monthly autoship program (called a Smart Ship) where you choose the product(s) you want shipped to you each month. You can easily create and then log into your Customer VIP Rewards account anytime and change the products on your monthly auto-ship or pause/cancel it. In blood, the major product of oxidative metabolism, CO2, reacts with water in the presence of carbonic anhydrase to form carbonic acid (H2CO3), which is relatively unstable and tends to dissociate and generate H+ and HCO3. The enzyme responsible for this is a zinc dependent enzyme is known as Carbonic Anhydrase and studies have shown that dietary deficiency of zinc reduces red blood cell carbonic anhydrase activity.
Other important zinc containing enzymes are carboxopeptidase, which helps break down protein. Zinc deficiency also impairs the synthesis of the protein Opsin, the precursor of Rhodopsin, which, if decreased, results in abnormal dark adaptation of the eye. Zinc is also required for the enzyme alcohol dehydrogenase, responsible for converting retinol to retinal, essential for eye function. Zinc is important for haemoglobin synthesis, a protein responsible for transporting oxygen in the blood. Metallothioneins are also examples of proteins with a zinc-binding motif. They are small metal-binding cysteine-rich proteins with a high affinity for zinc. They work together with zinc transporters, regulating free zinc concentrations in thecytosol, as described in THE PHYSIOLOGICAL, BIOCHEMICAL, AND MOLECULAR ROLES OF ZINC TRANSPORTERS IN ZINC HOMEOSTASIS AND METABOLISM . Zinc is an essential mineral supporting many areas of your health. Metabolics offers a range of Zinc supplements to support your nutritional needs. The types of zinc supplements you takemay remain a personal preference, or be based on some of the information provided. Common side effects of zinc include stomach upset, nausea, vomiting, and a metallic taste in the mouth. High doses of zinc can cause dizziness, headache, drowsiness, increased sweating, loss of muscle coordination, alcohol intolerance, hallucinations, and anemia.Osendarp SJ, van Raaij JM, Darmstadt GL, Baqui AH, Hautvast JG, Fuchs GJ. Zinc supplementation during pregnancy and effects on growth and morbidity in low birthweight infants: a randomised placebo controlled trial. Lancet. 2001;357(9262):1080-1085.
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