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In the 2018 election, Rauner was replaced by J.B. Pritzker, returning the state government to a Democratic trifecta. [59] In January 2020 the state legalized marijuana. [60]

Revised nomenclature for antigen-nonspecific T cell proliferation and helper factors". Journal of Immunology. 123 (6): 2928–9. Dec 1979. doi: 10.4049/jimmunol.123.6.2928. PMID 91646. Soybean Production by State 2008". Soy Stats. The American Soybean Association. 2009. Archived from the original on September 13, 2012 . Retrieved January 19, 2010. The first Farm Aid concert was held in Champaign to benefit American farmers, in 1985. The worst upper Mississippi River flood of the century, the Great Flood of 1993, inundated many towns and thousands of acres of farmland. [30] 21st century A COVID-19 safety message in the Chicago Loop Two Major League Baseball teams are located in the state. The Chicago Cubs of the National League play in the second-oldest major league stadium, Wrigley Field, and went the longest length of time without a championship in all of major American sport, from 1908 to 2016, when they won the World Series. [161] [162] The Chicago White Sox of the American League won the World Series in 2005, their first since 1917. They play on the city's south side at Guaranteed Rate Field. Illinois—Race and Hispanic Origin: 1800 to 1990". U.S. Census Bureau. Archived from the original on July 25, 2008.Maintenance of IL-17 producing cells, [36] increases angiogenesis but reduces CD8 T-cell infiltration a b "The Association of Religion Data Archives | County Membership Report". www.thearda.com. Archived from the original on November 12, 2013 . Retrieved November 12, 2013. Stebbins, Samuel. "How much gas tax adds to cost of filling up your car in every state". usatoday. 24/7 Wall Street. Archived from the original on March 31, 2019 . Retrieved March 31, 2019. Interleukin 8 is a chemokine produced by macrophages and other cell types such as epithelial cells, airway smooth muscle cells [25] and endothelial cells. Endothelial cells store IL-8 in their storage vesicles, the Weibel-Palade bodies. [26] [27] In humans, the interleukin-8 protein is encoded by the CXCL8 gene. [28] IL-8 is initially produced as a precursor peptide of 99 amino acids which then undergoes cleavage to create several active IL-8 isoforms. [29] In culture, a 72 amino acid peptide is the major form secreted by macrophages. [29] Though Illinois lies entirely in the Interior Plains, it does have some minor variation in its elevation. In extreme northwestern Illinois, the Driftless Area, a region of unglaciated and therefore higher and more rugged topography, occupies a small part of the state. Southern Illinois includes the hilly areas around the Shawnee National Forest.

Illinois also has more than twenty additional accredited four-year universities, both public and private, and dozens of small liberal arts colleges across the state. Additionally, Illinois supports 49 public community colleges in the Illinois Community College System.The United States Census Bureau found that the population of Illinois was 12,812,508 in the 2020 United States census, moving from the fifth-largest state to the sixth-largest state (losing out to Pennsylvania). Illinois' population slightly declined in 2020 from the 2010 United States census by just over 18,000 residents and the overall population was quite higher than recent census estimates. [83] Murzin AG, Lesk AM, Chothia C (Jan 1992). "beta-Trefoil fold. Patterns of structure and sequence in the Kunitz inhibitors interleukins-1 beta and 1 alpha and fibroblast growth factors". Journal of Molecular Biology. 223 (2): 531–43. doi: 10.1016/0022-2836(92)90668-A. PMID 1738162.

Pathieu, Diane (May 11, 2023). "COVID-19 public health emergency ends Thursday in US, Illinois". ABC 7 Chicago . Retrieved June 13, 2023. The term interleukin derives from ( inter-) "as a means of communication", and ( -leukin) "deriving from the fact that many of these proteins are produced by leukocytes and act on leukocytes". The name is something of a relic; it has since been found that interleukins are produced by a wide variety of body cells. The term was coined by Dr Vern Paetkau, University of Victoria.mononuclear phagocytes (and some other cells), especially macrophages following infection by virus(es)

After it was established in 1833, Chicago gained prominence as a Great Lakes port, and then as an Illinois and Michigan Canal port after 1848, and as a rail hub soon afterward. By 1857, Chicago was Illinois's largest city. [30] With the tremendous growth of mines and factories in the state in the 19th century, Illinois was the ground for the formation of labor unions in the United States. Since 2016, data for births of White Hispanic origin are not collected, but included in one Hispanic group; persons of Hispanic origin may be of any race. Historical Census Statistics on Population Totals By Race, 1790 to 1990, and By Hispanic Origin, 1970 to 1990, For The United States, Regions, Divisions, and States". Census.gov. July 25, 2008. Archived from the original on July 25, 2008 . Retrieved September 4, 2017. a b c "U.S. Wind Energy Projects—Illinois". American Wind Energy Association. September 30, 2009. Archived from the original on January 5, 2010 . Retrieved January 14, 2010. Jazz". Encyclopedia of Chicago. Archived from the original on May 4, 2012 . Retrieved May 19, 2012.

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Roman Catholicism percentage of Catholics statistics—states compared—People data on StateMaster". Statemaster.com. May 15, 2012. Archived from the original on May 30, 2012 . Retrieved May 19, 2012. Charles Mound, located in the Driftless region, has the state's highest natural elevation above sea level at 1,235ft (376m). Other highlands include the Shawnee Hills in the south, and there is varying topography along its rivers; the Illinois River bisects the state northeast to southwest. The floodplain on the Mississippi River from Alton to the Kaskaskia River is known as the American Bottom. Schindler R, Dinarello CA (1990). "Interleukin 1". In Habenicht A (ed.). Growth Factors, Differentiation Factors, and Cytokines. Berlin, Heidelberg: Springer. pp.85–102. doi: 10.1007/978-3-642-74856-1_7. ISBN 978-3-642-74856-1.